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ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:

1. Platelet neutralization tests are one of the confirmatory tests that can be used to determine if a patient has a circulating lupus antibody, or lupus anticoagulant. The principle in this test involved the use of a freeze-thawed platelet suspension that, when mixed with the patient plasma, will neutralize the anti-phospholipid antibodies (lupus anticoagulant) present and allow for a corrected aPTT result upon re-testing.
A patient has a history of repeated spontaneous abortion. Coagulation studies reveal an elevated APTT, normal PT, normal platelet function, and normal clotting time. Schistocytes were seen on the peripheral blood smear.
Which test should be performed to determine if the patient has lupus anticoagulant?

A) mixing studies with factor-deficient plasma
B) platelet neutralization test
C) antinuclear antibody test
D) Factor VIII assay

2. The liver is the primary target organ for the Hepatitis B virus (HBV). The inflammation caused by HBV can result in permanent liver damage, including cirrhosis, liver failure, and even hepatocellular carcinoma.
What is the primary target of the Hepatitis B virus?

A) Lungs
B) Heart
C) Liver
D) Blood cells

3. The patient's BUN is within normal range (5-20 mg/dL) while the creatinine is about five times the upper normal range (0.6-1.2 mg/dL). Gross elevations in creatinine are almost always accompanied by elevations in BUN when there is kidney impairment. Either the BUN or creatinine value in this case is incorrect. Both tests should be repeated.
A patient's BUN value is 15 mg/dl and his creatinine is 5 mg/dl. If this patient is not undergoing dialysis, what conclusion would you draw from these results?

A) patient protein intake is quite low
B) one of the values is in error
C) patient has suffered muscle deterioration
D) patient is in early stage of renal disease
E) patient is normal

4. Micro - Matching
1. Upper left image
Multi-celled, rough walled macroconidia with a tapered terminal cell
2. Upper right image
Dense aggregates of echinulate, brown-black conidia
3. Lower left image
Loose clusters of elliptical conidia arranged in a "diphtheroid" pattern
4. Lower right image
Chains of large, lemon-shaped annelloconidia

A) Scopulariopsis species
B) Acremonium species
C) Microsporum canis
D) Aspergillus niger

5. Flow cytometry employs a combination of fluorescent antibody tagging of cells and analysis with laser light scatter.
What principle(s) of flow cytometry are employed when performing immunophenotyping:

A) Impedance
B) Defraction gradients
C) Fluorescent antibody tagging and light scatter
D) Defraction gradients and impedance

Solutions: